Cytomegalovirus Preventive Strategies in Liver Transplant
نویسندگان
چکیده
منابع مشابه
Cost-effectiveness of different strategies of cytomegalovirus prophylaxis in orthotopic liver transplant recipients.
Cytomegalovirus (CMV) is an important cause of morbidity and mortality in liver transplant recipients and several different strategies of CMV chemoprophylaxis are in practice. A cost-effective analysis was performed to compare these strategies. A hypothetical cohort of liver transplant recipients was followed up for a year posttransplantation in a Markov model, as they made possible transitions...
متن کاملPreventive Strategies Against Cytomegalovirus and Incidence of α-Herpesvirus Infections in Solid Organ Transplant Recipients: A Nationwide Cohort Study.
We assessed the impact of antiviral preventive strategies on the incidence of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections in a nationwide cohort of transplant recipients. Risk factors for the development of HSV or VZV infection were assessed by Cox proportional hazards regression. We included 2781 patients (56% kidney, 20% liver, 10% lung, 7.3% heart, 6.7% others). Ov...
متن کاملA direct and indirect comparison meta-analysis on the efficacy of cytomegalovirus preventive strategies in solid organ transplant.
BACKGROUND Prophylactic and preemptive strategies are used to prevent cytomegalovirus (CMV) infections after solid organ transplant. We assessed the safety and efficacy of both strategies for CMV prevention. METHODS A DerSimonian and Laird random-effects model was used for pooling the data, and Q statistic and I(2) methods were used to assess statistical heterogeneity. RESULTS Twenty studie...
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The differential diagnosis of liver dysfunction after orthotopic liver transplantation can be difficult. Cytomegalovirus (CMV) hepatitis is one possibility. This report reviews our experience with 17 cases of pathologically proven CMV hepatitis following liver transplantation and demonstrates the need for percutaneous liver biopsies to establish the diagnosis. There were seven pediatric patient...
متن کاملPediatric Liver Transplant
The goals of post-transplant management are to manage and treat postoperative complications, and develop a balanced long-term immunotherapy regimen that minimizes infection and side effects but controls rejection. While modern immunosuppressant regimes have reduced rates of graft loss due to rejection, they impart major risks for infection, growth failure, metabolic complications, and malignanc...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2015
ISSN: 1600-6135
DOI: 10.1111/ajt.13267